新生儿呼吸机相关肺炎的病原菌分析

Analysis of pathogenic bacteria of ventilator-associated pneumonia in neonates

目的:探讨新生儿呼吸机相关肺炎(VAP)的病原学和药物敏感情况,指导临床用药。方法:符合VAP诊断标准的31例患儿的气道分泌物培养和药敏试验进行回顾性分析。结果:16例痰培养阳性,共检出细菌23株,其中革兰阴性杆菌12株,球菌6株,霉菌5株。结论:VAP的病原菌以革兰阴性菌为主,对亚胺硫霉素较敏感,其次为环丙沙星、头孢吡肟。混合感染和多重耐药是VAP的病原学特点。

Objective ：To investigate the etiology of ventilator-associated pneumonia（VAP） and its drug sensitivity condition ,so as to instruct the clinical treatment.Methods：The airway secretion euhure and drug sensitivity test in 31 sick children who met the diaguostie criterion of VAP were analysed retrospectively.Results：The sputum culture was positive in 16 cases,and 28 strains of bacterium were detected in all.Of 28 strains, 12 were gram-negative bacillus,6 eoeeus and 5 fungus.Conclusion：The main pathogenic bacteria of VAP are gram-negative bacteria,and are relatively sensitive to adriamyein and then eiprofloxaein and cefepime.The mixed infection and multiplet drug resistance are the etiological characteristics of VAP.