期刊文献+

凝血酶激活的纤溶抑制物与深静脉血栓形成相关分析

下载PDF
导出
摘要 目的:探讨凝血酶激活的纤溶抑制物(TAFI)与深静脉血栓(DVT)形成的关系。方法:应用发色底物法和ELISA法分别测定了30例DVT患者和30例正常对照者TAFI的活性及抗原。结果:DVT组TAFI的活性及抗原[TFAIAct(58.69±15.24)μg/ml,TAFI Ag(123.45±25.64)%]均较对照组[TAFI Act(30.15±9.36)μg/ml,TAFI Ag(69.35±24.13)%]显著增高(P<0.01)。结论:TAFI具有抑制纤溶的作用,可能与DVT形成有关。
出处 《中国误诊学杂志》 CAS 2008年第27期6596-6597,共2页 Chinese Journal of Misdiagnostics
  • 相关文献

参考文献2

二级参考文献12

  • 1Girolami A,Simioni P,ScaranoL,et al.Symptomatic combined homozygous factor Ⅻ deficiency and heterozygous factor Ⅴ Leiden[J].Thromb-Thrombolysis,2000,9(3):271-275.
  • 2Kuhli C,Scharrer I,Koch F,et al.Factor XII deficiency:a thrombophilic risk factor for retinal vein occlusion[J].Ophthalmol,2004,137(3):459-64.
  • 3Bouma BN, Marx PF, Mosnier LO, et al. Thrombin-activatable fibrinolysis inhibitor (TAFI, plasma procarboxypeptidase B, procarboxypeptidase R, procarboxypeptidase U ). Thromb Res, 2001,101:329-354.
  • 4Schroeder V,Chatterjee T, Mehta H, et al. Thrombin activatable fibrinolysis inhibitor (TAFI) levels in patients with coronary artery disease investigated by angiography. Thromb Haemost,2002,88 : 1020-1025.
  • 5Segev A,Hegele RA, Lau HK, et al. Thr325Ile polymorphism of the TAFI gene is related to TAFI antigen plasma levels and angiographic restenosis after pereutaneous coronary interventions. Thromb Res ,2004,114 : 137-141.
  • 6Henry M, Aubert H, Morange PE, et al. Identification of polymorphisms in the promoter and the 3' region of the TAFI gene: evidence that plasma TAFI antigen levels are strongly genetically controlled. Blood, 2001,97:2053-2058.
  • 7Treouet DA, Aubert H, Henry M, et al. Combined segregationlinkage analysis of plasma thrombin-activatable fibrinolysis inhibitor (TAFI) antigen levels with TAFI gene polymorphisms. Human Genetics ,2001,109 : 191-197.
  • 8Zorio E, Castello R, Falco C, et al. Thrombin-activatable fibrinolysis inhibitor in young patients with myocardial infarction and its relationship with the fibrinolytic function and the protein C system. Br J Haematol, 2003,122:958-965.
  • 9Morange PE, Henry M, Frere C, et al. Thr325IIe polymorphism of the TAFI gene does not influence the risk of myocardial infection. Blood ,2002,99 : 1878-1879.
  • 10Juhan-Vague I, Morange PE, Aubert H, et al. Thrombinactivatable fibrinolysis inhibitor antigen concentration and genotype in relation to myocardial infarction in the north and south of Europe. Arterioscler Thromb Vasc Biol,2002,22:867-873.

共引文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部