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肺炎支原体肺炎患儿外周血IgE、IL-13、IL-18水平的初步研究 被引量：12

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摘要 目的探讨肺炎支原体肺炎患儿外周血IgE、IL-13与IL-8的水平及其临床意义。方法118例病例均选自2003年1月至2004年1月问住院的患儿，符合支原体肺炎的诊断标准。入院患儿检测IgE、IL-13与IL-18及病原学检查。同时选择80例健康体检的婴幼儿作为正常对照组。结果肺炎支原体感染患儿血中IgE、IL-13与IL-18明显高于对照组。结论肺炎支原体感染可刺激机体产生特异性IgE，诱导Ⅰ型变态反应进而导致肺炎患儿出现晚期气道高反应。肺炎支原体感染发病机制与细胞免疫功能紊乱、外周血T淋巴细胞失衡有关。
作者 芦爱萍 刘冬华 吴赣华
机构地区 深圳市第五人民医院儿科
出处 《中国小儿急救医学》 CAS 2008年第1期66-67,共2页 Chinese Pediatric Emergency Medicine
关键词 肺炎支原体 IGE IL-13 IL-18 肺炎
分类号 R725.6 [医药卫生—儿科]
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参考文献7

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二级参考文献20

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二级引证文献154

中国小儿急救医学
2008年 第1期

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