腋淋巴结阴性乳腺癌血管内皮生长因子浓度与微转移相关性
摘要
乳腺癌从早期开始就表现为一种全身性疾病,该观点目前已被广泛接受。血行转移是乳腺癌转移的一条重要途径,血管内皮生长因子(VEGF)已经被认为是促使肿瘤新血管生成的最重要的生长因子之一,乳腺癌组织表达VEGF,乳腺癌患者的血清也能检测到VEGF。目前广泛认为,VEGF的表达是肿瘤复发转移的重要机制,通过阻断VEGF途径抗肿瘤血管生成的靶向治疗已经开始应用于晚期或复发性乳腺癌,
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
2008年第8期1087-1087,共1页
Chinese Journal of Experimental Surgery
基金
湖北省卫生厅科研基金资助项目(301140151)
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