摘要
目的:探讨不同孔径新型复合材料硅/磷酸钙植入兔下颌骨缺损区的成骨能力。方法:将3种不同孔径硅/磷酸钙(大孔型300μm、150μm及致密型)分别植入兔下颌骨缺损区。分别在术后3、6、12周取材进行大体、组织学观察及新骨形成的统计学分析。结果:3种不同孔径硅/磷酸钙在12周均能与邻近骨组织骨性结合:2种大孔型硅/磷酸钙新生骨面积百分比均显著大于致密型硅/磷酸钙(P<0.01)。结论:大孔型硅/磷酸钙骨引导性、成骨活性优于致密型硅/磷酸钙。
Objective： To study the osteointegration of calcium silicate/calcium phosphate with different pore sizes in mandibular defect regeneration. Methods： Calcium silicate/calcium phosphate with different pore sizes： macropores （150μm ,300μm） and compact ones,were implanted into mandibular defect of rabbits.Gross observation, histomorphological examination and area percentage of new bone formation were examined in 3,6 and 12 weeks postoperatively. Results： Solid osteointegration were observed in all experiment rabbits after 12 weeks. The area percentage of new bone formation induced by macroporous calcium silicate/ calcium phosphate was significantly greater than those of compact ones （P〈0.01）. Conclusion： Osteoinduction potentials of macroporous calcium silicate/calcium phosphate is better than compact ones.
出处
《口腔颌面外科杂志》
CAS
2008年第4期252-255,共4页
Journal of Oral and Maxillofacial Surgery
关键词
骨缺损
孔径
骨引导性
骨面积百分比
bone defect
pore size
osteoinductivity
osseous area percentage
