宫颈癌患者行卵巢移位术后卵巢功能的临床研究

Clinical Research on the Ovaries Function of Uterine Cervix Cancer Patients after Taking Ovary Transposition

目的探讨卵巢移位对年轻宫颈癌患者术后卵巢功能的影响。方法1997年5月—2005年11月对48例40岁以下宫颈鳞癌Ⅰb-Ⅱb患者施行卵巢移位术,其中40例在根治术中同时行卵巢移位术,8例在根治性放疗前行卵巢移位术,通过对血清性激素水平的监测评估术后卵巢功能。结果48例卵巢移位术前术后血清性激素水平差异无统计学意义(P>0.05),卵巢移位术后放疗组雌二醇水平(59.46±24.32)ng/L,虽较未放疗组(105.47±74.09)ng/L低(P<0.05),但仍显著高于根治性放疗组(17.68±9.43)ng/L(P<0.05)。结论对于年轻宫颈癌患者,卵巢移位术是一种安全有效的保留卵巢功能的方法。

Ovary transposition was conducted on 48 patients under age 40 with Ⅰb-Ⅱb uterine cervix carcinoma since May 1997 to November 2005, among which 40 received ovary transposition while taking radical correction and 8 received ovary transposition before the radical correction; their ovary function was evaluated through monitoring serum gonadal hormone level. [ Results] No significant difference was found in the serum gonadal hormone level among the patients before and after the ovary transposition （ P 〉 0.05 ） ; after the ovary transposition, the estradiol level of the radiotherapy group was lower than that of the non -radiotherapy group （ 105.47 ±74.09） ng/L （ P〈 0. 05 ）, but significantly higher than that of the radical radiation therapy group （17.68 ± 9.43 ） ng/L （ P 〈 0.05 ）. [ Conclusion ] Ovary transposition is a safe and effective method of remaining ovary function for the young uterine cervix Cancer patients.