吗啡染毒大鼠死后体内吗啡的分布研究

Postmortem distribution of morphiue in rats

作者采用免疫组织化学（PAP）法观察慢性吗啡染毒大鼠死后，在不同时间尸体内吗啡公布的变化。发现随着死后时间的延长，吗啡在大鼠CNS的分布无明显改变；其它内脏器官组织中吗啡分布则有明显改变；内脏脂肪组织原未查见吗啡，随死后时间延长，吗啡含量增加．证实大鼠染毒死后尸体内吗啡存在重分布现象。初步讨论了死后体内吗啡分布的变化与死后时间的关系，为吸毒致死后尸检取材提供依据。

The purpose Of the StUdy is to investigate the dis-tribution Of morphine in rats by immunohis-tochemistry(PAP).The results ShOWed that thecontent of morphine in CNS was Of little Change,and the content Of morphine in other tissuedecresed with prolonged time.Morhine inintraperitioneal fatty tissue ahowed a great increaseafter death.The study demonstrated that postmortendisrtabution Of morphine in rats had signifiCantChangeS at different time after .It may providea reason for better Choice of postmortem tissue indetecting addicts of morphine after death.