CD_4 T淋巴细胞分级表达与艾滋病合并肺结核影像征象相关性研究

Related research on the imaging features of AIDS with tuberculosis and CD_4 T lymphocyte count classification

目的探讨CD4T淋巴细胞分级表达与艾滋病(AIDS)合并肺结核影像征象的相关性。方法依照CD4T淋巴细胞数多少分为Ⅰ级和Ⅱ级,对56例AIDS合并肺结核螺旋CT征象与CD4T淋巴细胞分级表达进行相关性研究。结果原发性肺结核、单发空洞发生率与CD4T淋巴细胞分级表达呈正相关;斑片状和(或)实变影、多发空洞、多发结节、纵隔和(或)腋下淋巴结肿大发生率和继发性肺结核、右肺中叶及双肺下叶发生率与CD4T淋巴细胞分级表达呈负相关。结论AIDS合并肺结核病变特征与CD4T淋巴细胞的免疫功能损害有关,CD4T淋巴细胞表达越低,肺部影像征象越不典型。

Objective To explore the correlation between the imaging features of AIDS with tuberculosis and CD4 T lymphocyte classification expression. Methods CD4 T lymphocyte counts had been divided into grade Ⅰ and grade Ⅱ. The imaging features of fifty-six cases with AIDS complicated pulmonary tuberculosis patients were performed by CT scan. Resuits The incidence of the primary pulmonary tuberculosis, single cavitas had a positive correlation with CD4 T lymphocyte classifications expression, P 〈 0.05. The incidence of the patching or （and） large consolidation shadows, multi-cavitates, multiple nodules, mediastinum and （or） axillary lymphadenectasis, and the incidence of the secondary pulmonary tuberculosis, the middle lobe of right lung and the inferior lobi of bilateral lungs was correlated with the CD4 T lymphocyte classfications expression, P 〈 0. 05. Conclusion The features of AIDS with tuberculosis lesions character are relevant to CD4 T lymphocytes immune dysfunction. The pulmonary imaging manifestations are less typical if the expression leavels of the CD4 T lymphocyte are lower.