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ACE基因I/D多态性与老年充血性心力衰竭的关系 被引量：1

Association Between Polymorphism of Angiotensin-converting Enzyme Gene I/D and Congestive Heart Failure in Elderly Patients
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摘要 血管紧张素转换酶(ACE)是肾素-血管紧张素系统(RAS)的关键酶,其基因I/D多态性在不同种族、不同民族等正常人群中分布存在差异,与充血性心力衰竭(CHF)的易感性、严重性、药物的治疗效果及预后相关。现就近年来关于血管紧张素转换酶基因I/D多态性与老年充血性心力衰竭的关系进行综述。 Angiotensin-converting enzyme is the key enzyme in rennin-angiotensin system. The allele frequency of I/D polymorphism is significant different in different races and nations. This polymorphism has been found to associate with the susceptibility, severity, drag treatment and prognosis of congestive heart failure. This article reviewed the newest researches about the relation of I/D polymorphism in angiotensin-converting enzyme gene with congestive heart failure in elderly patients.
作者 李静 杨秀英
机构地区 潍坊医学院研究生部 潍坊医学院附属潍坊市人民医院保健科
出处 《医学综述》 2008年第17期2607-2609,共3页 Medical Recapitulate
关键词 血管紧张素转换酶 基因 心力衰竭 充血性 Angiotensin-converting enzyme Gene Heart failure, Congestive
分类号 R541.61 [医药卫生—心血管疾病] Q343 [生物学—遗传学]
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参考文献21

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二级参考文献32

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医学综述
2008年 第17期

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