血塞通对突发性耳聋的疗效及血液流变学指标的影响

Influence of Xuesaitong Injection on Curative Effect of Sudden Deafness and Hemorrheological Parameters

目的观察血塞通对突发性耳聋的疗效及血液流变学指标的影响。方法突发性耳聋患者103例(106耳),随机分成治疗组68例(70耳)和对照组35例(36耳)。对照组以氟桂利嗪胶囊、高压氧舱连续治疗12d,治疗组在此基础上每日加用血塞通400mg静滴,于疗程结束时评价疗效和血液流变学指标的变化。结果治疗组有效59耳,有效率84.3%;对照组有效13耳,有效率36.1%。两组疗效差异有显著性。治疗组治疗前后血液流变学多项指标明显改善,有显著差异,而对照组治疗前后血液流变学指标无明显改善。结论血塞通对突发性耳聋患者有显著疗效,且能使其血液流变学多项指标明显改善。

Objective To observe the influence of Xuesaitong injection on curative effect of sudden deafness and hemorrheological parameters. Methods 103 patients（ 106 ears） with sudden deafness were randomly divided into 2 groups： 68 patients （70 ears） in treatment group and 35 patients （36 ears） in control group. The patients in control group received flunarizine, hyperbaric oxygen, 12 days a course, while the patients in treatment group, besides treatments mentioned above, received intravenous injection of 400mg of Xuesaitong inejection once a day, 12 days a course. Curative effect and the change of the hemorrheological parameters were evaluated after a course of treatment. Results The effective rate of the treatment group was 84.3 %, and that of the control group was 36. 1%. There was a significant difference between the curative effect of the two groups. The treatment group had significantly improvement in hemorrheological parameters after treatment, while there was no notable difference in the control group. Conclusion Xuesaitong injection obviously improves curative effect of sudden deafness and hemorrheological parameters.