九味增智饮治疗血管性痴呆病气虚血瘀证30例临床观察

Therapeutic Effect of Jiuwei Zengzhi Decoction for Vascular Dementia with Qi Deficiency and Blood Stasis:An Observation of 30 Cases

目的:观察九味增智饮治疗血管性痴呆病(气虚血瘀证)的临床疗效。方法:将60例患者随机分为2组,治疗组30例予九味增智饮治疗,对照组30例口服喜得镇治疗,疗程均为3月。结果:临床疗效总有效率治疗组为96.67%,对照组为96.67%,2组比较,差异无显著性意义(P>0.05)。治疗后2组痴呆量表(HDS)积分、日常生活能力量表(ADL)积分均明显提高,与治疗前比较,差异均有非常显著性意义(P<0.01)治疗后第2、4、8、12周时治疗组副反应量表(TESS)评分均明显低于时照组,2组比较,差异有非常显著性意义(P<0.01)结论:九味增智饮治疗血管性痴呆病疗效与喜得镇相当,但副反应明显较后者轻。

Objective:To observe the therapeutic effect of Jiuwei Zengzhi Decoction(JZD) for vascular dementia(VD) with Qi deficiency and blood sta- sis.Methods:Sixty patients were equally randomized into 2 groups:the treatment group received JZD,and the control group received Hydergine Tablet. The treatment lasted 3 months.Results:The total effective rate was 96.67% in the treatment group, and 96.67% in the control group, the dif- ference being insignificant(P>0.05). After treatment,the scores of Hasegawa Dementia Scale (HDS) and Activity of Daily Life were increased in the two groups(P<0. 01 compared with those before treatment).The scores of Treatment Emergent Symptom Scale(TESS) were lower in the treatment group than those in the control group 2, 4, 8 and 12 weeks after treatment(P<0. 01). Conclusion: The therapeutic effect of JZD for VD is similar to Hy- dergine Tablet, and JZD has less side effects.