老年与非老年大肠癌的临床对比分析

A clinical comparative study on colorectal carcinoma between the elderly and the younger people

目的探讨老年人大肠癌的临床诊治特点。方法回顾性分析、比较本院1990年1月至2006年12月间收治的老年(≥60岁,n=139)与非老年<60岁,n=177)大肠癌手术治疗患者临床病理特征之间的差异。结果与非老年组相比,老年组中有肠癌家族史的比例较低,合并其他器官疾病的比例较高,右半结肠肿瘤较多,Dukes分期较晚,手术根治率低,术后并发症较多,上述差异均具有统计学意义(均P<0.05)。结论老年大肠癌如能早期发现,积极采取包括手术的综合治疗措施,仍能获得较理想的治疗效果。

Objective To investigate the characters of clinical diagnosis and treatment in elderly patients with colorectal carcinoma. Methods 139 elderly patients with colorectal carcinoma whose ages were more titan 60 years old and 177 control patients with colorectal carcinoma whose ages were less than 60 years old had been treated with surgical operation in our hospital from January 1990 to December 2006. Differences of clinical and pathologic characters between these two groups were analyzed and compared retrospectively. Results Compared to the control group, the elderly group contributed a smaller proportion of family heredity, a greater proportion of having co-existlng diseases, more advanced in Dukes classifications, more right colorectal carcinomas, lower operation radical cure rate and higher postoperative complications. （P 〈0.05 ）. Conclusion The ideal treatment effect can be achieved if colorectal carcinoma of the elderly patients is diagnosed earlier and suitable surgical operations are undertaken.