反相液相色谱中Z对小分子溶质色谱特征的表征

Z Value as a Characterization of Chromatographic Behaviour of Small Solutes in Reverse Phase Liquid Chromatography

对液相色谱中的一个新的表征参数Ｚ进行了多方面验证。证明Ｚ值在限定条件下可分别作为溶质种类、大小和空间效应及流动相特性的表征，并将Ｚ值与溶质的其他物理化学参数做了相互比较，又以非极性小分子烷基苯的同系物和极性小分子脂肪醇的同系物为例进行说明。

A new characterization parameter Z in reverse phase liquid chromatography has been studied. The results show that Z value is not only a characterization parameter for the kind, size and molecular structure of small solutes, but it is also for the mobile phase used. The Z values were also to compare with other physicochemical parameters of solutes, such as hydrophobic fragmental constant(lgf), Van der waals volume(V van·w ), molecular connectivity(X), apolar alkylbenzenes homologous and polar n alkyalcohels were used as examples to explain it.