摘要
目的:观察更昔洛韦治疗小儿手足口病的临床疗效。方法:将158例手足口病患儿随机分成治疗组和对照组,分别静脉给予更昔洛韦5mg·kg^-1·d^-1和利巴韦林10—15mg·kg^-1·d^-1,对临床症状和体征进行观察和分析。结果:治疗组临床症状和体征均较对照组消失早(P〈0.01)。结论:更昔洛韦治疗小儿手足口病疗程短,见效快,有明显疗效。
Objective:To observe the curative effect of ganciclovir on children with hand foot and mouth disease (HFMD). Method: 158 patients with HFMD were divided into two groups randomly. The treatment group were treated with ganciclovir 5 mg·kg^-1· d^-1 intravenously, and the control group were treated with ribavirin 10-15 mg· kg^ -1· d ^- 1 intravenously. In the process of treatment, the chang of symptoms and signs were observed everyday. Result: The clinical symptoms and signs of the patients in the treatment group disappeared earlier than that in the control group (P 〈0.01 ). Conclusion: Ganciclovir can reduce the treatment period and raise the curative without side effect in the children with HFMD.
出处
《药学与临床研究》
2008年第4期305-306,共2页
Pharmaceutical and Clinical Research
关键词
更昔洛韦
手足口病
小儿
Ganciclovir
Hand foot and mouth disease
Children