42例药品不良反应报告分析

ANALYSIS OF 42 CASES OF ADVERSE DRUG REACTIONS

目的:了解医院药品不良反应(ADR)发生的特点,促进临床合理用药。方法:对42例ADR患者的性别、年龄及药品的种类、给药途径、临床表现等进行统计分析。结果:42例患者中抗微生物药物引起的ADR22例(52.4%);中药制剂引起的ADR10例(23.8%);给药途径以静脉滴注为主,占69.0%(29例);主要的ADR类型为皮肤及附件损害,占66.7%(28例)。结论:药品不良反应与多种因素有关,应重视药品不良反应的报告和监测工作,促进临床合理用药。

Objective： To determine the characteristics of adverse drug reactions （ADR） in Chengdu Railway Branch Hospital and to promote rational clinical use of drugs. Methods ： All cases were analyzed in sex, age, drug type, drug administration, clinical manifestation, etc. Results ： Of the 42 ADR cases, 22 cases resulted from antibiotic drugs which accounted for 52.4%, 10 cases induced by preparations of traditional Chinese medicine which accounted for 23.8%, most cases（29 cases） resulted from intravenous injection （iv） which accounted for 69.0%. ADR most commonly manifested itself in the injury of skin and appendants, which accounted for 66.7 % （28 cases）. Conclusion：ADR are connected with several factors. ADR monitor must be strengthened in order to ensure rational drug use.