摘要
A high-pressure quartz crystal microbalance(QCM)apparatus was developed to investigate the absorption of carbon dioxide in two glassy polymer films—polystyrene(PS)and polyvinylpyrrolidone(PVP)at 40℃ and pressure up to 9.0 MPa.PVP was shown to have better CO2 absorption and chosen as the representative for supercritical impregnation of two model drugs—o-aminobenzoic acid and ibuprofen at 40℃ and pressure up to 8.0 MPa.It was found that the two impregnants were embedded into the polymer with a partition coefficient as high as 104 order of magnitude.Since the sub-microweighing technique established and utilized in this study was simple,convenient and accurate,it was believed that the technique could have wide and effective applications in supercritical impregnation processes.
A high-pressure quartz crystal microbalance（QCM）apparatus was developed to investigate the absorption of carbon dioxide in two glassy polymer films—polystyrene（PS）and polyvinylpyrrolidone（PVP）at 40℃ and pressure up to 9.0 MPa.PVP was shown to have better CO2 absorption and chosen as the representative for supercritical impregnation of two model drugs—o-aminobenzoic acid and ibuprofen at 40℃ and pressure up to 8.0 MPa.It was found that the two impregnants were embedded into the polymer with a partition coefficient as high as 104 order of magnitude.Since the sub-microweighing technique established and utilized in this study was simple,convenient and accurate,it was believed that the technique could have wide and effective applications in supercritical impregnation processes.
出处
《化工学报》
EI
CAS
CSCD
北大核心
2008年第8期2041-2045,共5页
CIESC Journal
基金
国家自然科学基金项目(20776065)
江苏省自然科学基金项目(BK2005077)
本科生能力提高项目(NFFTBSJ0630425)~~
