原发性支气管肺癌1345例统计分析

Statistical analysis of 1 345 patients with lung cancer

目的:探讨不同年龄段肺癌的病理及临床特征。方法:回顾性查阅新桥医院2001年1月至2007年12月间共1345例确诊原发性支气管肺癌患者的临床病理资料,以Statistica6.0及Excel2003进行统计分析。结果:在全部1345例肺癌患者中,男性所占比重较大,男女比例约为4:1(78.07%:21.93%),其发病高峰年龄段均于50～59岁,分别占男性和女性患者的36.00%及31.53%,病理类型总体分布为腺癌:鳞癌:小细胞癌=37.99%:35.99%:15.61%,其中女性患者以肺腺癌(62.03%)居多,男性以肺鳞癌(42.38%)居首位,不同病理类型及性别构成比例分布在不同年份之间差异无显著性,肺腺癌所占比例随年龄增大呈现下降趋势。结论:肺癌发病率与患者年龄相关,男女比例约为4:1,腺癌居于首位,但随年龄增大所占比例减小。

Objective To investigate the clinical and pathological characteristics of patients with lung cancer. Methods The clinical and pathological data of 1 345 patients with primary bronchogenic carcinoma in Xinqiao Hospital from January 2001 to December 2007 were retrospectively analysis by the Statistica 6.0 and Excel 2003. Result 78.07% of the patient were male and 21.93% were female,with a male to famale ratio of approximately 4 to 1. The incidence peak was ranged from 50 to 59 years, with a rate of 36.00% in male and 31.53% in female. 37.99% of pateient were pathologically diagnosed with adenocarcinoma, 35.99% were squamous cell carcinoma, and 15.61% were small cell lung cancer. Most of the female patients （62.03%） had adenocarcinoma while the majority of the male patients （42.83%） had squamous cell carcinoma. There were no significant differences in the pathologic types and gender ration among the seven years. The incidnce rate of adenocarcinoma decreased with age. Conclusions The increased rate of lung cancer is associated with age, with a male to famale ratio of approximately 4 to 1. Adenocarcinoma is the most common form in lung cancer but its incidence rate declines with age.