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沙美特罗联合氟替卡松治疗支气管哮喘疗效分析 被引量:10

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摘要 目的:观察沙美特罗联合氟替卡松(舒利迭)治疗支气管哮喘的疗效。方法:把87例确诊为支气管哮喘的患者分为吸入糖皮质激素加长效β2受体激动剂的舒利迭组37例,β2受体激动剂组26例,糖皮质激素组24例。治疗后对肺功能、临床症状、药物副作用等方面进行评价。结果:舒利迭组用药后肺功能改善及临床症状消失及好转皆明显优于其他组,且副作用相对较少。结论:吸入沙美特罗联合氟替卡松治疗哮喘临床疗效良好,能改善肺通气功能,降低气道高反应性,改善生存质量。
出处 《实用医学杂志》 CAS 2008年第18期3236-3237,共2页 The Journal of Practical Medicine
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参考文献8

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二级参考文献5

  • 1Pichon A, Roulaud M, Denjean A, et al. Airway tone during exercise in healthy subjects: effects of salbutamol and ipratorpium bromide. Int J Sports Med,2005;26(5):321.
  • 2Mak JC,Nishikawa M,Barnes PJ.Glucocorticocorticosteroids increase beta2-adrenergic receptor transcription in human lung.Am J Physiol,1995;268(1):41.
  • 3Bpusquet J, Jeffery PK, Busse WW, et al. Asthma. From bronchoconstriction to airways inflammation and remodeling. Am J Respir Crit Care Med,2000;161(5):1720.
  • 4Woolcock A, Lundback B, Ringdal N, et al. Comparison of addition of salmeterol to inhaled steroid with doubling of the dose of inhaled steroids. Am J Respir Crit Care Med,1996;153(5):1481.
  • 5Aziz I,Lipworth BJ.A bolus of inhaled budesonide rapidly reverses airway subsensitivity and beta2-adrenoceptor down regulation after regular inhaled formoteral. Chest,1999;115(3):623.

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