期刊文献+

外科手术治疗2型糖尿病:肠-胰岛轴机制和展望 被引量:16

下载PDF
导出
摘要 1982年,Pories等在手术治疗病态肥胖症时偶然发现合并有2型糖尿病的患者接受减肥手术后.体重显著减轻的同时血糖也快速恢复了正常。且不再需要采取任何降糖措施维持。从而开创了一条外科手术治疗2型糖尿病的新途径。Ferchak等于2004年对肥胖症,减肥手术和2型糖尿病的回顾性研究中指出胃旁路术(gastric bypass,GBP)和胆胰转流术(biliopancreatic diversion。BPD)与90%~100%糖耐量异常患者和80%~90%早期2型糖尿患者的术后糖代谢改变相关。
出处 《实用医学杂志》 CAS 2008年第18期3268-3269,共2页 The Journal of Practical Medicine
  • 相关文献

参考文献19

  • 1Pories W J, Swanson M S, MacDonald K G, et al. Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus [J]. Ann Surg, 1995,222(3) :339-350.
  • 2Ferchak C V, Meneghini L F. Obesity,bariatric surgery and type 2 diabetes a systematic review [J]. Diabetes Metab Res Rev, 2004,20 (6) : 438-445.
  • 3Patriti A, Facchiano E, Donini A. Effect of duodenal-jejunal exclusion in a non- obese animal model of type 2 diabetes : a new perspective for an old disease [J]. Ann Surg, 2004,240(2) : 388-389.
  • 4张士虎,苗毅.胃旁路术对非肥胖型糖尿病大鼠的降糖作用[J].南京医科大学学报(自然科学版),2006,26(3):176-179. 被引量:13
  • 5Cummings D E, Overduin J, Foster- Schubert K E. Gastric bypass for obesity : mechanisms of weight loss and diabetes resolution [J]. J Clin Endocrinol Metab, 2004,89(6) : 2608-2615.
  • 6Meneghini L F. Impact of bariatric surgery on type 2 diabetes [J]. Cell Biochem Biophys, 2007,48(2-3) :97-102.
  • 7Rubino F, Forgione A, Cummings D E, et al. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes [J]. Ann Surg, 2006,244 ( 5 ) : 741-749.
  • 8Alexandrides T K, Skroubis G, Kalfarentzos F. Resolution of diabetes mellitus and metabolic syndrome following Roux-en-Y gastric bypass and a variant of biliopancreatic diversion in patients with morbid obesity [J]. Obes Surg, 2007,17 (2).176-184.
  • 9Rubino F, Gagner M. Potential of surgery for curing type 2 diabetes mellitus [J]. Ann Surg, 2002,236(5) :554-559.
  • 10Flatt P R. Effective surgical treatment of obesity may be mediated by ablation of the lipogenic gut hormone gastric inhibitory polypeptlde (GIP): evidence and clinical opportunity for development of new obesity-diabetes drugs [J]? Diab Vasc Dis Res, 2007,4(2) : 151-153.

二级参考文献15

  • 1Smith S,Edwards CB,Goodman GN.Changes in diabetic management after Roux-en-Y gastric bypass[J].Obes Surg,1996,6(3):345-348
  • 2White S,Brooks E,Jurikova L,et al.Long-term outcomes after gastric bypass[J].Obes Surg,2005,15(2):155-163
  • 3Scott E,Frank L,Stanley Klein.Effects of obesity surgery on non-insulin-dependent diabetes mellitus[J].Arch Surg,2002,137(10):1109-1117
  • 4Rubino F,Gagner M,Gentileschi P,et al.The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism[J].Ann Surg,2004,240(2):236-242
  • 5Rubino F,Gagner M.Potential of surgery for curing type 2 diabetes mellitus[J].Ann Surg,2002,236(5):554-559
  • 6UK Prospective Diabetes Study (UKPDS) Group.Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)[J].Lancet,1998,352(5):837-853
  • 7Sjostrom L,Lindroos AK,Peltonen M,et al.Lifestyle,diabetes,and cardiovascular risk factors 10 years after bariatric surgery[J].N Engl J Med,2004,351 (26):2683-2693
  • 8Mingrone G,DeGaetano A,Greco AV,et al.Reversibility of insulin resistance in obese diabetic patients:role of plasma lipids[J].Diabetologia,1997,40(5):599-605
  • 9Hickey MS,Pories WJ,MacDonald KG,et al.A new paradigm for Type 2 diabetes mellitus:could it be a disease of the foregut[J]? Ann Surg,1998,227(5):637-644
  • 10Gentileschi P,Kini S,Catarci M,et al.Evidence-based medicine:open and laparoscopic bariatric surgery[J].Surg Endosc,2002,16(5):736-744

共引文献12

同被引文献107

引证文献16

二级引证文献24

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部