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尿激酶型纤溶酶原激活剂及其受体与胃癌关系的研究进展 被引量：2

Research progression of relationship between uPA and uPAR and stomach carcinoma
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摘要 尿激酶型纤溶酶原激活剂(uPA)及其受体(uPAR)是纤溶系统的重要组成部分,主要通过激活纤溶酶降解细胞外基质,促进肿瘤的浸润与转移。此文就它们与胃癌之间的关系及在临床中的应用作一综述,旨在为胃癌的诊断和治疗提供新方法、开辟新途径。 uPA and uPAR are important ingredients of fibrolysis system, which can degrade extracellular matrix and promote the infiltration and metastasis of tumors mainly through activing fibrinolysin. This review discusses the relationship between uPA and uPAR and stomach carcinoma and the clinical application,in order to provide new approach and develop new way for the diagnosis and therapy of stomach carcinoma.
作者 张科 卜平
机构地区 扬州大学医学院中西医结合实验室
出处 《国际消化病杂志》 CAS 2008年第4期312-314,共3页 International Journal of Digestive Diseases
关键词 尿激酶型纤溶酶原激活剂(uPA) 尿激酶型纤溶酶原激活剂受体(uPAR) 胃癌 相关性 Urokinase-type plasminogen activator uPA receptor Stomach carcinoma Correlation
分类号 R735.2 [医药卫生—肿瘤]
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  • 1赵仲生,茹国庆,马杰.IGF-Ⅱ和HGF mRNA表达与胃癌微血管密度的关系[J].中华肿瘤杂志,2004,26(11):673-677. 被引量：27
  • 2Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature, 2001 ,411: 375-379.
  • 3Champelovier P, Boucard N, Levacher G, et al. Plasminogen- and colony-stimulating factor-1-associated markers in bladder carcinoma:diagnostic value of urokinase plasminogen activator receptor and plasminogen activator inhibitor type-2 using immunocytochemical analysis. Urol Res, 2002,30:301-309.
  • 4Rosario L, Varmi M, Salani D, et al. Endothelin-1 induces tumor proteinase activation and invasiveness of ovarian carcinoma cells. Cancer Res, 2001,61:8340-8346.
  • 5lgarashi N, Kubota T, Otani Y, et al. Preventive effect of matrix metalloproteinase inhibitor, R-94138, in combination with mitomycin C or cisplatin on peritoneal dissemination of human gastric cancer cell line TMK-1 in nude mice. Jpn J Cancer Res, 1999,00: 116-121.
  • 6Park IK, Kim BJ, Goh YJ, et al. Co-expression of urokinase-type plasminogen activator and its receptor in human gastric-cancer cell lines correlates with their invasiveness and tumorigenicity.Int J Cancer,1997,71:867-873.
  • 7Choi YK, Yoon BI, Kook YH, et al. Overexpression of urokinase-type plasminogen activator in human gastric cancer cell line (AGS) induces tumorigenicity in severe combined immunodeficient mice. Jpn J Cancer Res, 2002,93: 151-156.
  • 8刘庆华,陈峻青.人胃癌细胞腹膜粘附影响因素的实验研究[J].中华肿瘤杂志,1999,21(5):336-338. 被引量：5
  • 9蔡华,孔昭如,陈红梅.胃癌基质金属蛋白酶-2与血管生成的关系[J].癌症,2002,21(1):25-28. 被引量：21
  • 10Jian-XianYu,Xiao-TunZhang,Yong-QiangLiao,Qi-YiZhang,HuaChen,MeiLin,ShantKumar.Relationship between expression of CD105 and growth factors in malignant tumors of gastrointestinal tract and its significance[J].World Journal of Gastroenterology,2003,9(12):2866-2869. 被引量：10

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国际消化病杂志
2008年 第4期

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