Silensor阻鼾器治疗阻塞性睡眠呼吸暂停综合征临床观察

Clinical Observation on the Therapeutic Efficacy of Silensor in Obstructive Sleep Apnea Syndrome

目的探讨Silensor阻鼾器对阻塞性睡眠呼吸暂停综合征(OSAS)的临床疗效。方法对17例确认为阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome,OSAS)患者佩带阻鼾器治疗,并在佩带前后用CT扫描观察患者上气道截面积的变化,同时采用夜间多导睡眠仪监测低通气指数(HI)、呼吸暂停指数(AI)和呼吸紊乱指数(AHI),观察临床治疗效果。结果观察对象上气道截面积均有增大,最小值从0.82cm2增加到1.70cm2;口咽上部截面积平均值由1.04cm2增加到1.93cm2;夜间多导睡眠仪图显示各项指标均较治疗前明显降低,差异具有统计学意义(P<0.05)。结论Silensor阻鼾器可使咽喉的空间扩大,空气流动的速度减慢,对治疗阻塞性睡眠呼吸暂停综合征有一定疗效。

Objective To observe the therapeutic efficacy of silensor in obstructive sleep apnea syndrome（OSAS）. Methods 17 patients with OSAS were treated with mandibular advancement appliance named silensor and re-examined by PSG monitoring equipment at night. The changes in the sleep disorder indexes were analyzed. The upper airway structure were determined by CT before and after treatment. Results 17 patients responded to the appliance therapy. There were significant increases in upper airway area from 0.82 to 1.70 cm^2 and in upper oral-pharynx area from 1.24 to 1.93 cm^2 at average. However, the HI, Apnea index and AHI significantly decreased （ P 〈 0.05 ）. Conclusion The silensor is an effective alternative that could benefit the patients with mild OSAS.