眼睑皮脂腺癌治疗的研究进展

Recent advances on treatment of sebaceous gland carcinoma of eyelid

眼睑皮脂腺癌是最常起源于睑板腺和睫毛皮脂腺的恶性肿瘤,居眼睑恶性肿瘤的第2位。由于其高复发率和高转移率,已经受到人们的重视。最新研究和临床经验表明,早期发现,早期诊断,以手术为主,化疗、放疗、冷冻为辅的综合性治疗是提高眼睑皮脂腺癌存活率的关键。但是,随着现代治疗手段的应用,逐渐倾向于避免眼眶内容摘除的保守性治疗方法,这些方法有望减少复发和转移的发生率。本文就眼睑皮脂腺癌的治疗新进展作一综述。

Sebaceous gland carcinoma of eyelid is a malignant neoplasm that most usually arises in the meibomian glands of the tarsus and in the Zeis gland. It is also the second most common malignancy of the eyelid. Because of its high recurrence and metastasis, it has already gotten more attention. The recent research and clinical experience demonstrate that the key point to improve survive rate is early detection and diagnosis, surgery adjuvant with chemotherapy, radiotherapy and cryotherapy in sebaceous gland carcinoma patients. However, with more recently employed treatment, there is a tendency to avoid exenteration and other conservative treatments. It is hoped that these modern therapeutic approaches will result in fewer cases of recurrence and metastasis. This article makes a brief overview of the recent advances on treatment of sebaceous gland carcinoma of eyelid.