液基薄层细胞学检测在诊断和治疗宫颈病变中的临床应用

A Study on the Clinical Evaluation of Thinprep Cytologic Test in Diagnosis and Treatment of Cervical lesions

目的:探讨液基薄层细胞学检测(TCT)在宫颈病变检查及治疗中的临床价值。方法:对1616例自愿患者进行TCT检测,予以Betheasda系统(TBS)细胞学分类;同期3002例患者行子宫颈阴道细胞涂片巴氏染色及巴氏5级分类。分别对TCT检测提示阳性的179例和子宫颈阴道细胞涂片阳性的227例进行阴道镜下活检,进行病理学诊断,并根据检查结果予以相应治疗。结果:TCT检测阳性179例,与病理检查符合121例(67.60%);巴氏涂片阳性227例,与病理检查符合62例(27.31%)。结论:TCT在宫颈病变的检测中,有较高的阳性检出率,与病理检查有较高的符合率,可提供早期发现宫颈癌变和癌前病变的信息,指导临床合理治疗,具有重要的临床实用价值。

Objective：To research the clinical evaluation of thin prep cytological test in diagnosis and treatment of cervical le sions. Methods：A total of 1616 volunteers examined by thinprep cytologic test（TCT） and classficated with the Betheasda system （TBS）. And 3002 volunteers examined by cervical smears and classficated with Pap＇s classification at the same time, By TCT selected 179 positive cases and by cervical smears 227 positive cases were then diagnosed by cervical biopsy punched under the instruction of colostomy, and treated according to the results. Results：in 179 positive cases by TCT, 121 cases were coordinate with pathological （67.60%）, in Pap＇s smear 277positive cases, 62 cases were the same with pathological （27.31 %）. Conclusion：TCT in cervical lesions has a higher detective rate and higher coincidence rate with pathological diagnosis. It can help phy sician to recognize early cervical carcinoma and precancerous lesions of cervix, define the reasonable therapeutic approach, has important clinical evaluation.