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CD_(28)在疾病治疗中的作用研究进展 被引量：8

Study Progress of the Role of CD_(28) in Therapy of Diseases
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摘要 CD28是一种重要的参与机体适应性免疫应答中T细胞活化的共刺激分子,它参与T细胞活化信号的转导,使T细胞活化、增殖、启动和维持免疫应答。若无共刺激信号,抗原特异性T淋巴细胞或凋亡或被诱导呈无能状态。CD28共刺激途径在器官移植排斥反应、自身免疫性疾病、肿瘤、炎性反应中均起重要作用,阻断这一通路可为这些疾病的治疗开辟一条新的途径,具有广阔的前景。
作者 张仪 韩波
机构地区 山东大学附属山东省立医院小儿心脏科
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2008年第15期1204-1206,共3页 Journal of Applied Clinical Pediatrics
关键词 CD28 T细胞 共刺激分子
分类号 R392 [医药卫生—免疫学]
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参考文献17

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二级参考文献20

  • 1蒋毅,万康林,耿震,侯学霞.中国莱姆病伽氏疏螺旋体蛋白免疫印迹法诊断标准的研究[J].中华微生物学和免疫学杂志,2005,25(7):594-598. 被引量：11
  • 2朱文文,王晓涛.DNA损伤检测—单细胞凝胶电泳技术的研究[J].微量元素与健康研究,2007,24(3):6-7. 被引量：21
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共引文献12

同被引文献100

引证文献8

二级引证文献19

实用儿科临床杂志
2008年 第15期

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