摘要
利用超声波的空化效应对大粒径酵母β-葡聚糖(SCG)进行超声修饰,修饰后的SCG(C-SCG)呈现分布均匀的单颗粒状,粒径分布带宽明显变窄,平均粒径由原来的56.49μm降低到2.33μm。由于粒径的变化会给SCG免疫功效带来一定的影响,故对其免疫功效进行了考察:与修饰前的SCG(N-SCG)相比,修饰后的SCG使Con A诱导小鼠淋巴细转化率提高了42.35%;血清CH50提高了28.89%;NK细胞活性提高了78.10%,免疫功效得到显著增强。
The macroparticle β-glucans from Saccharomyces cerevisiae （SCG） were modified by ultrasonication in order to get microparticle SCG. After ultrasonical treatment, the equably singal particulates of SCG were homogeneous and it＇s average diameter reduced from 56.49 um to 2.33 um. Because the diameter change of SCG bring some influences to it＇s immune activity, the immunoactivity of N-SCG and C-SCG were tested. The results showed that, the lymphocyte proliferation, the hemolytic level and the activity of NK cells of C-SCG groups increased 42.35%, 28. 89% and 78.10%, respectively,compared to that of N-SCG groups.
出处
《食品与生物技术学报》
CAS
CSCD
北大核心
2008年第4期79-84,共6页
Journal of Food Science and Biotechnology
基金
国家科技部国际合作重大项目(2001DFBA0007)
关键词
Β-葡聚糖
超声修饰
免疫活性
β-glucans
ultrasonic modification
immunoactivity
