正电子显像剂11C-匹兹堡化合物B的化学合成及其临床应用
Chemical synthesis and clinical application of a new positron imaging agent 11C- Pittsburgh compound- B
摘要
阿尔茨海默病（AD）是一种严重影响老年人生活质量的常见疾病。11C-匹兹堡化合物B（11C—PIB）作为新型β-淀粉样蛋白（Aβ）正电子显像剂，能够特异性地检出AD的特征性病理学改变，为AD的早期诊断、早期治疗乃至疗效评价提供了潜在的可能性。
Alzheimer disease（AD）seriously influenced the quality of life in elderly. As a new positron imaging agent binding with β-amyloid, 11C-Pittsburgh compound-B can specifically detect characteristic pathological changes of AD. It provides the potential possibility of early diagnosis and treatment, effect evaluation in AD.
出处
《国际放射医学核医学杂志》
2008年第3期158-161,共4页
International Journal of Radiation Medicine and Nuclear Medicine
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