摘要
随着放射治疗的广泛应用，临床上的放射性损伤也逐渐受到重视。电离辐射对中枢神经系统细胞、分子的作用是一个复杂、渐进的过程，目前其确切机制尚不完全清楚。探讨电离辐射作用下神经元、神经胶质细胞、血管内皮细胞及血脑屏障的损伤和修复，以及分子水平改变的可能机制和神经保护策略的研究进展，以期为临床上防治放射性神经损伤提供有益的思路。
Along with radiation treatment extensively applied, radiation injury also is valued gradually.The effect of radiation to the cellular and molecular of central nervous system （CNS） is a complicated and moderately advanced process and the mechanism is remains incompletely clear yet. Inquiring into the possible mechanism of the CNS including the injury and the restoration of neuron, neuroglia cells, endotheliocyte cell and blood-brain barrier and the molecular level of change induced by radiation, so as to provide beneficial thought for preventing and curing radiation injury clinically. Some neuroprotective strategies are also addressed in the review.
出处
《国际放射医学核医学杂志》
2008年第3期179-182,共4页
International Journal of Radiation Medicine and Nuclear Medicine
基金
国家自然科学基金资助项目（30670638）
