摘要
以3,6-双(3,5-二甲基吡唑)-1,2,4,5-四嗪为起始原材料,经肼基取代、氧化脱氮生成了3,6-二氯-1,2,4,5-四嗪,通过红外、核磁、质谱以及元素分析鉴定了化合物的结构,在优化合成工艺条件下,两步总收率达到70%,在超低温的条件下对产品进行了精制,纯度达到了99.2%以上。
3,6-Dicholo-1,2,4,5-tetrazine（BCT） was synthesized from 3,6- bis（3,5-dimethylpyrazol-l-yl）-1 ,2,4,5- tetrazine after substitution and oxidation. Its structure was characterized by IR, MS, ^13C NMR and elemental analysis. In addition, the synthetic procedure of BCT was optimized. The best condition of oxidation reaction was obtained as follows： reaction time was 15 min, content of water 0.08%, and the overall yield 70%. The purity of the product was 99.2% after the refined at the uhralow temperature.
出处
《精细化工中间体》
CAS
2008年第4期53-55,共3页
Fine Chemical Intermediates
关键词
四嗪
纯度
合成
tetrazine
purity
synthesis
