下段胆管癌的外科治疗

Surgical treatment of distal bile duct carcinoma

目的探讨下段胆管癌外科手术治疗的方法及其效果。方法回顾性总结和分析51例下段胆管癌行外科治疗的临床资料。根治性胰十二指肠切除术28例,减黄性手术23例。结果总体中位生存时间20个月;根治性胰十二指肠切除术、减黄性手术生存期分别为32,8个月;根治性胰十二指肠切除术5年生存率17.8%,减黄性手术为0;根治性胰十二指肠切除术的疗效明显优于减黄性手术(P<0.01)。结论对下段胆管癌积极行根治性胰十二指肠切除术,能延长生存期,改善患者生活质量。

Objective To study the methods and outcome of surgical treatment of distal bile duct carcinoma. Methods The clinical data of 51 eases of distal bile duct carcinoma who underwent surgery were analyzed retrospectively. Of them, 28 cases received radical pancreaticoduodenectomy, and 23 cases had internal bile duct drainage procedures. Results The total average survival time was 20 months. The mean survival time of radical and drainage operation was 32 months and 8 months respectively. Postoperative 5-year survival rate in radical panereaticoduodenectomy group was 17. 8% , and in drainage group was 0. The outcome of radical pancreaticoduodenectomy group was significantly better than that of internal bile duct drainage procedures group （ P 〈 0.01 ）. Conclusions The results showed that radical pancreaticoduodenectomy for distal bile duet carcinoma can prolong survival and is effective in improving quality of life.