黛力新与劳拉西泮治疗广泛性焦虑症的对照研究

A comparative study of Deanxit and Lorazepam in the treatment of generalized anxiety disorder

目的:探讨黛力新治疗广泛性焦虑症的疗效及安全性。方法:将66例广泛性焦虑症患者随机分为两组,分别给予黛力新和劳拉西泮治疗6周。采用焦虑自评量表(SAS)、Hamilton焦虑量表(HAMA)和副反应量表(TESS)评定疗效及不良反应。结果:黛力新与劳拉西泮治疗广泛性焦虑症均有显著疗效,两组间疗效差异无显著性,黛力新组不良反应少于劳拉西泮。结论:黛力新与劳拉西泮治疗广泛性焦虑症疗效相似,黛力新更安全,具有依从性好,不良反应少,心血管系统不良反应轻微,患者易于接受的特点,尤适于老年期广泛性焦虑症患者。

Objective： To compara the efficacy and safety of Deanxit and Lorazepam in the treatment of generalized anxiety disorder, nethods：A total of 66 patients with generalized anxiety disorder were randomly divided into the Deanxit group （n = 33 ） and the Lorazepam group （n =33） for 6 weeks. SAS ,HAMA and TESS were used to measure the efficacy and safety before and after treatment. Results： Deanxit and Lorazepam are both effective for treatment of generalized anxiety disorder. There was no significant difference on efficacy between two groups. The side effects in Deanxit group were significantly lower than in the Lorazepam group. Conclusions： Deanxit is safe and effective agents for treating generalized anxiety disorder.