期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

α-生育酚与自由基DPPH^.的反应机理研究 被引量：12

The Mechanism of a Reaction between α-Tocopherol and DPPH^. Studied by NMR and ESR Spectroscopy
下载PDF
导出
摘要 通过NMR产物分析方法确认α-生育酚与DPPH·在DMSO中的反应最终产物结构为醌式.此外,对该反应过程的ESR实验证实α-生育酚与DPPH·反应的计量比为1∶2.由此可以进一步推断:α-生育酚与DPPH·反应的分子机制为两步过程. In this paper the reaction product of α-tocopherol and DPPH^. radical in DMSO was analyzed by NMR spectroscopy, and found to have a tetraalkylbenzoquinonoid group. The reactive ratio of α-tocopherol to DPPH^. was confirmed to be 1 ： 2 with ESR spectroscopy. Based on these two results, it is proposed that the reaction pathway of α-tocopherol and DPPH^. has two steps.
作者 杨盈 严宝珍 聂舟 王梅 田秋 刘扬
机构地区 北京化工大学理学院 中国科学院化学研究所、分子动态与稳态结构国家重点实验室
出处 《波谱学杂志》 CAS CSCD 北大核心 2008年第3期331-336,共6页 Chinese Journal of Magnetic Resonance
基金 国家自然科学基金资助项目(30570446)
关键词 NMR ESR 反应机理 Α-生育酚 DPPH^. NMR ESR reaction mechanism α-tocopherol DPPH^.
分类号 O482.53 [理学—固体物理]
  • 相关文献

参考文献14

  • 1Brigelius-Flohe R, Traber M G. Vitamin E: function and metabolism[J]. Faseb J, 1999, 13(10): 1 145- 1 155.
  • 2Tucker J M, Townsend D M. Alpha-tocopherol, Roles in prevention and therapy of human disease[J]. Biomed Pharmacother, 2005, 59: 380-387.
  • 3Mukai K, Okabe K, Hosose H. Synthesis and stopped-flow investigation of antioxidant activity of tocopherols. Finding of new tocopherol derivatives having the highest antioxidant activity among phenolic antioxidants[J]. J Org Chem, 1989, 54: 557-560.
  • 4Barclay L R C, Vinqvist M R, Mukai K, et al. Chain-breaking phenolic antioxidants: steric and electronic effects in polyalkylchromanols, tocopherol analogs, hydroquinones, and superior antioxidants of the polyalkyl- benzochromanol and naphthofuran class[J]. J Org Chem, 1993, 58: 7 416-7 420.
  • 5Hussain H H, Babic G, Durst T, et al. Development of novel antioxidants: Design, synthesis, and reactivity [J]. JOrgChem, 2003, 68:7 023-7 032.
  • 6Zhou Nie, Ke Jian Liu, Chuan-Jian Zhong, etal. Enhanced radical-scavenging activity by antioxidant-functionalized gold nanoparticles: A novel inspiration for development of new artificial antioxidant[J]. Free Radic Bio Med, 2007, 43:1 243-1 254.
  • 7Yin Huiyong. Quest for better antioxidants: a commentary on “Enhanced radical-scavenging activity by antioxidant-functionalized gold nanoparticles: A novel inspiration for development of new artificial antioxidant”[J]. Free Radic Bio Med, 2007, 43:1 229-1 230.
  • 8Strohschein S, Pursch M, Lubda D, et al. Shape selectivity of C30 phases for RP-HPLC separation of tocopherol isomers and correlation with MAS NMR data from suspended stationary phases[J]. Anal Chem, 1998, 70(1): 13-18.
  • 9华玉新,张建晋,宁永成.二维INADEQUATE谱在δ—维生素E上的应用[J].波谱学杂志,1989,6(3):294-298. 被引量：1
  • 10Luca C, Ionita P, Caproiu T, et al. Interphase processes involving hydrazine derivatives Ⅳ [J]. Rev Roum Chim, 1998, 43(1): 25-30.

同被引文献162

引证文献12

二级引证文献207

波谱学杂志
2008年 第3期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部