摘要
目的探讨肺炎支原体(MP)感染与毛细支气管炎的相关性,分析其临床特点。方法对186例毛细支气管炎患儿血清采用酶联免疫法(ELISA)MP-IgM检测,MP-IgM阳性为MP感染(感染组),MP-IgM阴性为对照组,对两组进行比较分析。结果感染组64例(34.4%),其中年龄<6个月13例(20.3%),~2岁51例(79.7%),冬春发病38例(59.4%),夏秋26例(40.6%)。对照组122例,其中年龄<6个月78例(63.9%),~2岁44例(36.1%),冬春发病112例(91.8%),夏秋10例(9.2%)。两组发病年龄和发病季节均有显著性差异(P<0.01)。两组患儿均有咳嗽、喘憋及呼吸困难,与对照组比较,MP感染组中高度发热62例(96.9%)、肺部X线片状阴影48例(75%),均高于对照组,有显著性差异(P<0.01)。CRP、白细胞总数(WBC)两组无显著性差异。并发症发生率,MP感染组18例(28.1%),对照组19例(15.5%),P<0.05。结论以中高度发热,且持续时间较长,肺部X线有片状阴影的毛细支气管炎患儿,应疑为MP感染及时进行MP抗体的检查,早期作出诊断与治疗。
Objective To study the relation olitis and mycoplasmas pneumonia (MP) in infants. of the clinical features on bronchi- Methods The blood serum MP-IgM of 186 young children with bronchiolitis were detected with ELISA test, according to results of MP-IgM were divided into MP-IgM positive group and MP-IgM negative group.The clinical features in two groups were conducted comparative analysis. Results In 186 patients with bronchiolitis 64 cases were MP-IgM positive(34.4%), age under 6 months was 13 cases (20.3%), from 6 months to 2 years 51 cases (79.7%), at the onset 38 cases (59,4%) were in winter and spring, 26 cases (40.6%) in summer and autumn. MP-IgM negative group was 122 cases, under 6 months was 78 cases(63.9), 6 months to 2 years 44 cases (36.1%), 112 cases(91.8%) in winter and spring, 10 cases(9.2%) in summer and autumn. In positive group the fever of mid-high was 62 cases (96.9%), CRP positive rate 21.9%(14 cases), WBC over 10 × 10^9/L 10 cases(15.6%), and the shadow area of chest in the roentgenogram was found in 48 cases (75%). The incidence of complication in positive group was 18 cases(28.1%), and negative group only 19 cases(15.5%)(P〈0.01). Conclusion The bronchiolitis in young children have higher fever with longer period dyspnea and the shadow area of chest etc. may raise the suspition of MP and detecte the MP-IgM in serum in time to get early diagnosis and treatment.
出处
《实用心脑肺血管病杂志》
2008年第8期21-23,共3页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease