布托啡诺与曲马多用于剖宫产产妇术中及术后寒颤治疗的观察

Effects of Butorphanol and Tramadol Used for Shivering in Women Undergoing Caesarean Section

目的比较布托啡诺与曲马多用于剖宫产产妇术中及术后寒颤治疗的安全性和有效性。方法50例剖宫产手术产妇（均为腰硬联合麻醉，ASAⅠ～Ⅱ）随机分为两组（n=25），分别经静脉给药，观察产妇术中及术后寒颤情况，实验组（Ⅰ组）为布托啡诺（0．01mg／kg），对照组（Ⅱ组）为曲马多（1mg／kg），分别记录用药前及用药后3.5min寒颤的评分和不良反应。结果两组产妇均于用药后5min寒颤停止，但对照组（Ⅱ组）出现恶心、呕吐及复发寒颤不良反应发生率较实验组（Ⅰ组）高，两组有统计学差异（P〈0．05）。结论布托啡诺（0．01mg／kg）比曲马多（1mg／kg）更优于治疗剖宫产产妇术中及术后寒颤。

Objective To compare the clinical effectiveness of butorphanol and tramadol on chills in women undergoing caesarean section. Methods Fifty parturient women with shivering（ all under combined-spinal epidural anesthesia, ASAⅠ -Ⅱ） were divided randomly into two groups：the control group （group Ⅰ） , treated with tramadol（1mg/kg,iv） and the experiment group（group Ⅱ ） ,treated with butorphanol （0.01mg/kg, iv）. The scores of shivering and medication adverse effects at the time before the treament and at the 3rd,5th min after treatment were recored. Results There was no significant difference between the two groups on treating shivering at the time before the treatment and at the 3rd,5th min after treatment , but there were several adverse effects in group Ⅱ, no adverse effect was found in group Ⅰ. Conclusion Butorphanol（0.01mg/kg,iv） is better than tramadol（1mg/kg,iv） used for shivering in women undergoing caesarean section.