期刊文献+

儿童慢性胰腺炎遗传学研究进展

下载PDF
导出
摘要 慢性胰腺炎(chronic pancreatitis,CP)是由于各种原因引起的胰腺局部或弥漫性炎性病变,使胰腺发生实质性损害,形成假性囊肿,胰腺内外分泌功能进行性衰退。临床表现为反复发作或持续性腹痛,体重减轻,腹泻,黄疸,糖尿病等。随着分子生物学和遗传学的发展,该病的遗传因素越来越受到人们的关注。
出处 《临床小儿外科杂志》 CAS 2008年第4期55-57,68,共4页 Journal of Clinical Pediatric Surgery
  • 相关文献

参考文献3

二级参考文献43

  • 1Theeraphong Pho-Iam,Wanna Thongnoppakhun,Pa-Thai Yenchitsomanus,Chanin Limwongse.A Thai family with hereditary pancreatitis and increased cancer risk due to a mutation in PRSS1 gene[J].World Journal of Gastroenterology,2005,11(11):1634-1638. 被引量:3
  • 2程祖建,杨滨,刘奇才,江凌,谢海花,欧启水.一个2型糖尿病家系中新发现的线粒体DNA G7444A突变分析[J].遗传,2007,29(4):433-437. 被引量:6
  • 3[1]Whitcomb DC,Gorry MC,Preston RA,Furey W,Sossenheimer MJ,Ulrich CD,Martin SP,Gates LK Jr,Amann ST,Toskes PP,Liddle R,McGrath K,Uomo G,Post JC,Ehrlich GD.Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene.Nat Genet 1996; 14:141-145
  • 4[2]Witt H,Luck W,Hennies HC,Classen M,Kage A,Lass U,Landt O,Becker M.Mutations in the gene encoding the serine protease inhibitor,Kazal type 1 are associated with chronic pancreatitis.Nat Genet 2000; 25:213-216
  • 5[3]Sharer N,Schwarz M,Malone G,Howarth A,Painter T,Super M,Braganza J.Mutations of the cystic fibrosis gene in patients with chronic pancreatitis.N Engl J Med 1998; 339:645-652
  • 6[4]Pitchumoni CS.Familial pancreatitis.In:Pai KN,Suman CR,Varghese R,editors.Pancreatic diabetes.Geoprinters:Trivandrum,1970:46-48
  • 7[5]Mohan V,Chari ST,Hitman GA,Suresh S,Madanagopalan N,Ramachandran A,Viswanathan M.Familial aggregation in tropical fibrocalculous pancreatic diabetes.Pancreas 1989; 4:690-693
  • 8[6]Chandak GR,Idris MM,Reddy DN,Mani KR,Bhaskar S,Rao GV,Singh L.Absence of PRSS1 mutations and association of SPINK1 trypsin inhibitor mutations in hereditary and non hereditary chronic pancreatitis.Cut 2004; 53:723-728
  • 9[7]Chandak GR,Idris MM,Reddy DN,Bhaskar S,Sriram PV,Singh L.Mutations in the pancreatic secretory trypsin inhibitor gene (PSTI/SPINK1) rather than the cationic trypsinogen gene (PRSS1) are significantly associated with tropical calcific pancreatitis.J Med Genet 2002; 39:347-351
  • 10[8]Mahurkar S,Idris MM,Reddy DN,Bhaskar S,Rao GV,Thomas V,Singh L,Chandak GR.Association of cathepsin B gene polymorphisms with tropical calcific pancreatitis.Gut 2006; 55:1270-1275

共引文献27

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部