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雷米芬太尼、丙泊酚靶控输注在小儿腺样体、扁桃体切除术的应用

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摘要 目的:探讨雷米芬太尼、丙泊酚靶控输注在小儿腺样体、扁桃体切除术的临床效果。方法:30例3~10岁ASAⅠ~Ⅱ级择期行腺样体、扁桃体切除手术患儿,采用雷米芬太尼3μg/ml(Minto模式)、丙泊酚3μg/ml(Marsh模式)的血浆浓度,诱导时间为0min,进行靶控输注(TCI)。观察麻醉前(T0)、注药后5min(T1)、气管插管后即刻(T2)、插管后5min(T3)、10min(T4)、30min(T5)、气管拔管时(T6)的血压、心率变化情况。记录停药后患儿呼吸、意识恢复时间,停药至拔管时间。观察术中知晓,术后恶心、呕吐情况。结果:注药后5min血压、心率都有一定程度下降(P﹤0.05),但气管插管后恢复到麻醉前水平,术中生命体征平稳。停药至呼吸恢复时间(7.1±3.4)min,停药至意识恢复时间(10.2±6.4)min,停药至拔管时间(13.2±6.7)min。所有患儿无术中知晓,3例发生术后恶心、呕吐。结论:雷米芬太尼、丙泊酚靶控输注用于小儿腺样体、扁桃体切除术安全有效。
出处 《中国医药导报》 CAS 2008年第25期71-71,128,共2页 China Medical Herald
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