氯霉素对沉积物生源要素生物地球化学循环的影响

Effects of chloramphenicol on biogeochemical cycle of biogenic elements in marine sediment

研究了氯霉素对沉积物中细菌总数、碱性磷酸酶活性及沉积物呼吸作用的影响表明氯霉素对沉积物细菌总数的影响呈现显著的浓度效应,在低浓度时影响不大,但在高浓度时抑制作用很显著;氯霉素在高浓度下对碱性磷酸酶活性具有抑制作用,且随着药物浓度的增加和时间的延长抑制作用加大;氯霉素对沉积物呼吸作用强度的影响,表现为非持续性的影响,尤其对于低浓度氯霉素来说,随着降解或者抗性种群的增加,呼吸作用逐渐恢复正常。而高浓度氯霉素对呼吸作用的影响时间则要长一些,影响程度也更大一些。

The effects of chloramphenicol on bacterial density, respiration and AlkalinePhosphatase activity in marine sediment were studied in laboratory by simulation experiments. The effects on bacterial density-were dependent on the chloramphenicol concentration. Chloramphenicol with high concentration inhibited the bacteria growth during the whole incubation process. Chloramphenicol has the significant effects on AlkalinePhosphatase activity in marine sediment at high concentration, and these effects were enhanced with the increase of concentrations. Chaloramphenicol has the non-durative effect on the respiration in marine sediment at low concentration, the respiration recovered gradually due to the resistance of heterotrophic bacteria to chloramphenicol. The high concentration has longer and larger effects on the respiration in marine sediment, comparing with the low concentration,.