女性年龄相关的血清护骨素参考值及与其他种族的比较

Age-related reference value of serum osteoprotegerin in female as compared with other races

测定647例成年健康女性（年龄20～81岁）的血清护骨素浓度并与其他种族进行比较。结果显示血清护骨素与年龄呈正相关（r=0．276，P〈0．01），绝经前血清护骨素的几何平均值显著低于围绝经期和绝经后。在中年期本组女性的护骨素显著高于奥地利女性和冰岛女性，在老年期则相反。

Serum osteoprotegerin （OPG） concentration was measured in 647 healthy female adults （aged 20-81 years） , and was compared with that of other races. The serum OPG was positively correlated with age （ r = 0. 276, P 〈0.01 ）. The geometric mean value of serum OPG in premenopausal women was significantly lower than those in perimenopausal and postmenopausal women. The serum OPG in middle-aged Chinese women was significantly higher than those in middle-aged Austrian and Icelandic, but this was quite contrary to the results obtained in old-aged women.