摘要
Xp11.2易位性肾癌是2004年WHO肾细胞癌病理组织学分类中新增的类型。虽然其总体发病率很低,但在儿童肾癌患者中约1/3为此类肾癌。它的临床表现、病理组织学特点、生物学行为及预后都有别于其它类型的肾癌。目前关于Xp11.2易位性肾癌的报道少见。本文对近年来有关Xp11.2易位性肾癌的研究作一综述,分别对其分型、流行病学特点、临床及病理组织学特点、诊断、治疗及预后等方面进行初步总结。
Xp11.2 translocation renal cell carcinoma (RCC) is a newly identified category of RCC described in the 2004 WHO Classification of Kidney Tumors. Although the incidence is very rare, it accounts about one third of pediatric RCCs. It is different from other RCCs in clinical manifestations, histopathologic features, biological behaviour and prognosis. At present, Xp11.2 translocation RCC has seldom been reported. This review analyzed recent researches on Xp11.2 translocation RCC, described its classification and summarized the characteristics of epidemiology, clinical manifestations, histopathology, diagnosis, treatment and prognosis.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
2008年第9期1006-1008,共3页
Chinese Journal of Cancer
关键词
肾肿瘤
Xp11.2易位
融合基因
分型
诊断
治疗
Renal neoplasm
Xp11.2 translocation
Fusion gene
Classification
Diagnosis
Therapy