妊娠期TORCH感染与妊娠结局的相关性分析

Related analysis of TORCH and pregnancy during pregnancy

目的了解妊娠期TORCH感染状况与不良妊娠结局之间的关系。为本地区开展出生缺陷的预防和干预提供数据及建议。方法采用酶联免疫吸附实验(ELISA)检测孕妇血清中TORCH-IgM抗体,对阳性孕妇进行追踪,并随访其妊娠结局。结果1328例受检孕妇中,血清TORCH-IgM阳性33例,总阳性率2.48%。继续妊娠24例,不良妊娠结局16例,占66.67%。结论TORCH感染可致不良妊娠结局,也是造成出生缺陷常见的不良因素。孕前和孕期进行TORCH血清学筛查,并给予适当干预,可减少不良妊娠的发生和预防出生缺陷。

Objective To investigate the relationship between TORCH infection and adverse pregnancy outcome during pregnancy and provide data and recommendations for birth defects intervention. Methods TORCH - IgM antibody in the serum of pregnant women was examined by ELISA. The women with positive result were followed up and the outcome of their pregnancy was collected. Results Of 1 328 pregnant women, 33 were found TORCH - IgM positive, the positive rate was 2.48%. 24 of 33 TORCH - IgM positive pregnant women continued their pregnancy and 16 of them were found adverse pregnancy outcome, accounting for 66.67%. Conclusion TORCH infection is associated with adverse pregnancy outcome. It is also a common adverse factor causing birth defects. TORCH infection should be screened pre - pregnancy and during pregnancy. Appropriate interventions can reduce the occurrence of adverse pregnancy and prevent birth defects.