摘要
探讨肝癌发生发展和转移复发的分子机制,寻找早期诊断肝癌、预测转移的生物标记和干预治疗的靶点,已成为当今肝癌研究的热点.随着后基因组时代的来临,蛋白质组学为涉及多基因、多蛋白的肝细胞癌研究创造了新的契机.本文就肝细胞癌的蛋白质组学研究进展作简要综述.多基因、多蛋白的肝细胞癌研究创造了新的契机.本文就肝细胞癌的蛋白质组学研究进展作简要综述.
At present, studies of hepatocellular carcinoma focus on investigating the molecular mechanism of carcinogenesis, development, metastasis and reccurrence and seeking biological markers for early diagnosis and metastasis prediction and targets for interfering therapy. In the postgenome era, proteomics provides novel insights into the research of hepatocellular carcinoma, which is controlled by multi-genes and multi- proteins. In this paper we reviewed the recent progress in proteomic study of hepatocellular carcinoma.
出处
《世界华人消化杂志》
CAS
北大核心
2008年第22期2487-2492,共6页
World Chinese Journal of Digestology
基金
国家高技术研究发展计划(863计划)
No.2007AA02Z479~~
