摘要
整合素连接激酶(ILK)是一种丝氨酸/苏氨酸蛋白激酶,参与多种信号通路,在调节细胞周期、基质积聚、胚胎发生、纤维化疾病、肿瘤发生进展中都起重要作用。近年研究发现ILK与肾小球疾病、肾小管间质纤维化和肾血管疾病等密切相关。
Integrin-linked kinase is a serine/threonine-protein kinase, which participate in many signaling pathways. It plays an important roll in cell cycle, groundmass accumulation, embryogenesis, fibrosis disease, tumorigenesis and tumor progression. Recent studies showed that ILK is closely related to renal glomerular disease, nephrie tubule-interstitial fibrosis, renal vascular disease and so on.
出处
《国际内科学杂志》
CAS
2008年第8期489-492,共4页
International Journal of Internal Medicine
关键词
肾疾病
整合素连接激酶
Kidney disease
Integrin-linked kinase
