摘要
目的:观察姜黄素提取物体外对流感病毒H1N1、H3N2的抑制作用。方法:用狗肾细胞(MDCK)观察姜黄素体外对A型流感病毒H1N1亚型、A型流感病毒H3N2亚型病毒的直接杀灭作用。结果:姜黄素最大无毒浓度为12.5g/L,对H1N1有效抑制浓度为6.25g/L,对H3N2有效抑制浓度为1.56g/L。结论:姜黄素提取物确有明显的抗H1N1、H3N2复制作用。
Objective:To investigate the inhibitory effect of curcumin on influenza virus HIN1 and H3N2 in vitro, Methods:The directly killing role of cureumin extract in vitro to influenza virus type A subtype H1N1 and H3N2 was evaluated by the canine kidney cells (MDCK), Results:The largest non toxic concentration of curcumin extract was 12, 5g/L and the effective inhibitory concentration to H1N1 and H3N2 was 6, 25G/1 AND 1,56g/L respectively, Conclusion: Curcumin extract have directly killing effect on H1N1 and H3N2 infections.