门诊高血压患者合并空腹血糖受损患病率及影响因素分析

Investigation and analysis of the prevalence and risk factors for impaired fasting glucose in outpatients with essential hypertension

目的探讨门诊原发性高血压患者空腹血糖受损患病率及影响因素。方法对2004年2月至2007年1月于本院门诊连续就诊的1026例原发性高血压患者[其中男531例，女495例，年龄15—87（51．6±12．5）岁]进行病史询问，血压、身高、体重、腰围、臀围、空腹血糖、血脂等指标的测量，并进行统计学分析。结果高血压患者空腹血糖总异常率及空腹血糖受损患病率分别为38．5％和30．5％。高血压患者中血糖正常组与空腹血糖受损组的性别构成比、收缩压、BMI、腰臀围比、血糖、TG、TC差异有统计学意义（P〈0．05）。进入logistic回归模型的有性别、糖尿病家族史、TC及LDL—C。结论门诊高血压患者空腹血糖受损患病率高于健康人群，且可能与性别、糖尿病家族史、血脂代谢异常有关。

Objective To evaluate the prevalence of impaired fasting glucose （IFG） in outpatients with essential hypertension and the influencing factors. Methods 1026 essential hypertensive outpatients aged 15 - 87 years[531 males and 495 females, mean age （51.6 ± 12. 5 ） years] who visited Xuanwu hospital between February 2004 and January 2007 were recruited in the study. Their medical history, blood pressure, height, weight, waist circumferences （ WC ） , hip circumference （ HC ） , fasting plasma glucose （FPG） , TC, TG, LDL-C, HDL-C were detected and analyzed. Results The abnormal rate of FPG in hypertensive outpatients was 38.5% and incidence of IFG was 30. 5%. The differences of gender,systolic blood pressure, BMI, waist-to-hip ratio （WHR）, TG, TC between the normal glucose group and the IFG group were significant. Gender, family history of diabetes mellitus, TC and LDL-C enter into the logistic regression model （P 〈 0. 05 ）. Conclusions The detection rate of IFG is high in hypertensive outpatients and it is related with gender, family history of diabetes mellitus and disorders of lipid metabolism.