氯化钾静脉滴注致婴儿过敏反应

Anaphylactic reaction following intravenous infusion of potassium chloride in an infant

1例5月龄女婴,因感染性腹泻伴轻度脱水,静脉滴注10%葡萄糖注射液250 ml+10%氯化钠注射液8 ml+10%氯化钾注射液3 ml。静脉滴注5 min后,患儿出现寒战、发热、呼吸困难。停止输液,给予地塞米松治疗后好转。第2天又输入同样液体,再次发生过敏反应。第3天停用氯化钾,其他药物不变,继续补液,未出现过敏反应。

A 5-month-old girl with infectious diarrhea accompanied by mild dehydration was administered with an IV infusion of 250 ml of glucose 10% mixed with 8 ml of sodium chloride 10% and 3 ml of potassium chloride 10%. Five minutes later, the girl developed chill, fever and dyspnea. The infusion was discontinued. Her condition improved after treatment with dexamethasone. The next day, the girl was given the same fluid again, then anaphylactic reaction reappeared. On day 3, potassium chloride was stopped and other drugs was unchanged. The fluid therapy was continued and anaphylactic reaction did not occur.