运动与肌球蛋白重链研究综述

The Review of Training and Myosin Heavy Chain

肌球蛋白作为骨骼肌纤维内主要的收缩蛋白和调节蛋白,对于骨骼肌纤维的收缩特性起重要作用,肌球蛋白重链是肌球蛋白重要组成,它有多种亚型表达,不同亚型收缩特性存在显著差异,研究发现,当外界刺激条件变化时,骨骼肌纤维肌球蛋白重链亚型组成可以改变,骨骼肌纤维收缩特性在肌球蛋白重链组成改变时发生显著变化,因此,研究不同运动条件下骨骼肌纤维肌球蛋白重链组成的变化对于深刻理解运动影响骨骼肌收缩性能具有重要意义。

Myosin is a primary protein, which has the contraction character of the skeletal fibres. As a dominating part of myosin, myosin heavy chain has many kinds expression of isoforms, there is remarkable difference among them. Some evidence has shown that myosin heavy chain isoforms can be transformed from one kind to another, meanwhile, the contraction character of the skeletal fibre altered simultaneously. Therefore, the study of transformation among myosin heavy chain isoforms under the condition of training is crucial for understanding the change of the contraction quality of skeletal fibre under the same condition.