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活性氧、钙和心力衰竭 被引量：3

Reactive oxygen species and calcium signaling in heart failure
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摘要 活性氧信号和钙信号广泛存在于机体内,两者相互作用,共同参与调节机体多种生理功能及病理过程。本文对这两个信号系统之间的相互作用及相关机制、在心力衰竭过程中的作用及可能的临床应用前景进行了综述。 Reactive oxygen species （ROS） and calcium signal constitute the most important intracellular signaling systems that participate in the regulation of multitude cellular functions. Here we briefly review interactions between the two prominent signaling systems, their integrated effects on heart failure, and their potentials for therapeutic interventions.
作者 颜媛 张会亮 方华强 郑铭 程和平 张荣利
机构地区 北京大学分子医学研究所
出处 《生命科学》 CSCD 2008年第4期528-539,共12页 Chinese Bulletin of Life Sciences
基金 国家自然科学基金(30630021 30770870 30500182) "973"计划(2007CB512100)
关键词 活性氧 钙 心力衰竭 reactive oxygen species calcium heart failure
分类号 Q463 [生物学—生理学]
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  • 1Krippeit-Drews P, Britsch S, Lang F, Drews G. Effects of SH-group reagents on Ca^2+ and K^+ channel currents of pancreatic B-cells. Biochem Biophys Res Commun 1994; 200: 860-6.
  • 2Pei ZM, Murata Y, Benning G, Thomine S, Klusener B, Allen G J,et al. Calcium channels activated by hydrogen peroxide mediate abscisic acid signalling in guard cells. Nature 2000; 406: 731-4
  • 3Hidalgo C, Bull R, Behrens MI, Donoso P. Redox regulation of RyR-mediated Ca^2+ release in muscle and neurons. Biol Res 2004;37: 539-52.
  • 4Xu L, Eu JP, Meissner G, Stamler JS. Activation of the cardiac calcium release channel (ryanodine receptor) by poly-S-nitrosylation. Science 1998; 279: 234-7.
  • 5Meissner G. Regulation of mammalian ryanodine receptors. Front Biosci 2002; 7: D2072-80.
  • 6Oba T, Kurono C, Nakajima R, Takaishi T, Ishida K, Fuller GA,et al. H2O2 activates ryanodine receptor but has little effect on recovery of releasable Ca^2+ content after fatigue. J Appl Physiol 2002; 93: 1999-2008.
  • 7Favero T, Zable AC, Abramson JJ. Hydrogen peroxide stimulates the Ca^2+ release channel from skeletal muscle sarcoplasmic reticulum. J Biol Chem 1995; 270: 25557-63.
  • 8Suzuki YJ, Cleemann L, Abernethy DR, Morad M. Glutathione is a cofactor for H2O2-mediated stimulation of Ca^2+-induced Ca^2+ release in cardiac myocytes. Free Radic Biol Med 1998; 24: 318-25.
  • 9Suzuki Y J, Ford GD. Superoxide stimulates IP3-induced Ca^2+ release from vascular smooth muscle sarcoplasmic reticulum. Am J Physiol 1992; 262: H114-6.
  • 10Missiaen L, Taylor CW, Berridge MJ. Spontaneous calcium release from inositol trisphosphate-sensitive calcium stores. Nature 1991; 352: 241-4.

共引文献6

同被引文献41

  • 1徐瑞霞,李建军.氧化型低密度脂蛋白胆固醇与动脉粥样硬化[J].中国医学前沿杂志（电子版）,2012,4(8):33-37. 被引量：12
  • 2柴怡,丁建花,李皓,胡刚.盐酸埃他卡林对H_2O_2所致PC12细胞损伤的保护[J].中国临床药理学与治疗学,2005,10(4):377-381. 被引量：2
  • 3王焱,王永志,邢红云,周君富.急性病毒性心肌炎患者体内氧化应激反应及损伤[J].新疆医科大学学报,2005,28(9):838-841. 被引量：4
  • 4冯达应,陈晓平.心房颤动与炎症和氧化应激[J].心血管病学进展,2006,27(3):352-355. 被引量：8
  • 5刘树森 魏影允.鼠肝线粒体内膜H-ATP酶ATP合成反应动力学[J].Acta Biochinica et Biophysica Sinica（生物化学与生物物理学报：英文版）,1987,19(3):241-251.
  • 6Saotome M,Safiulina D and Szabadkai G. Bidirectional Ca^2+- dependent control of mitochondrial dynamics by the Miro GTPase. PNAS,2008,105(52) :20728-20733.
  • 7Bantseev V, Sivak JG. Confocal laser scanning microscopy imaging of dynamic TMRE movement in the mitochondria of epithelial and superficial cortical fiber cells of bovine lenses. Mol Vis, 2005,11 : 518-523.
  • 8Gun X, Macleod GT, Wellington A, et al. The GTPase dMiro is required for axonal transport of mitochondria to Drosophila synapses. Neuron, 2005,47(3 ): 379-393.
  • 9Rintoul GL,Bennett V J, Papaconstandinou NA,et al. Nitric oxide inhibits mitochondrial movement in forebrain neurons associated with disruption of mitochondrial membrane potential. J Neurochem, 2006,97( 3 ) : 800-806.
  • 10Yi M,Weaver D, Hajnoczky G. Control of mitochondrial motility and distribution by the calcium signal:a homeostatic circuit. J Cell Biol,2004, 167:661-672.

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生命科学
2008年 第4期

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