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一氧化氮荧光分子探针 被引量：3

Fluorescent Probes for Sensing Nitric Oxide
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摘要 一氧化氮(NO)在生物体中扮演重要的角色,对其选择性识别引起了人们极大的兴趣。本文综述了两类NO荧光分子探针的研究进展,即含金属离子的NO荧光分子探针:如Co(Ⅱ)、Fe(Ⅱ)、Ru(Ⅱ)、Rh(Ⅱ)和Cu(Ⅱ)配合物作为荧光打开的NO分子探针;邻苯二胺类荧光分子探针:如2,3-二氨基萘(DAN)、二氨基荧光素衍生物(DAFs)、二氨基罗丹明衍生物(DARs)、硼二吡咯甲基衍生物(BODIPY)和三碳菁衍生物(DAC)等。 Nitric oxide （NO）, a reactive free radical, regulates a variety of biological processes. Therefore its accurate detection and quantification are critical to understand health and disease. In this review, two types of fluorescent probes for NO are mainly described, namely, metal-based sensors, which utilizing NO binding to the metal center, such as Co（ Ⅱ ）, Fe（ Ⅱ）, Ru（ Ⅱ ）, Rh（ Ⅱ ） and Cu（ Ⅱ） complexes as turn-on fluorescent NO sensors; Organic moleculebased sensors, which are mainly diamine fluorescent indicators for NO, such as DAN, DAFs, DARs, BODIPY and DACs.
作者 张灯青 赵圣印 刘海雄
机构地区 东华大学化学化工与生物工程学院
出处 《化学进展》 SCIE CAS CSCD 北大核心 2008年第9期1396-1405,共10页 Progress in Chemistry
关键词 一氧化氮 荧光检测 含金属离子的荧光探针 芳香二胺 nitric oxide fluorescent detection metal-based fluorescent probes aromatic diamino compounds
分类号 O657.3 [理学—分析化学] O659.32 [理学—分析化学]
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共引文献104

同被引文献17

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化学进展
2008年 第9期

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