新发传染病诊断及鉴别诊断预警系统研究

Establishment of a warning system for diagnosis and differential diagnosis of emerging infectious diseases

目的建立我国尚未报道的新发传染病(EID)诊断及鉴别诊断预警系统。方法系统研究我国目前尚未报道的EID 文献资料,综合分析并提取主要临床特征,采用信息化技术,建立其诊断和鉴别诊断预警系统。结果建立的诊断和鉴别诊断预警系统具有信息的完整录入、查询、统计、分析和网络预警等功能。应用该系统对49种感染性疾病、314份病例进行初步验证,结果显示第一诊断符合率61.9%;前3位提示率78.1%;前5位提示率86.6%。结论新发传染病的诊断及鉴别诊断预警系统功能强大,使用方便、灵活,扩充性强,对病例比较准确地提示可能的诊断及鉴别诊断,提供针对性的进一步检查内容及治疗原则,特殊病例可通过电子疫情报告系统及时上报,可以提前预警 EID。

Objective To establish a warning system for diagnosis and differential diagnosis of emerging infectious diseases （EID） which were not reported at home. Methods Literatures about EID from Medline not reported at home and other sources were reviewed systematically and key clinical features were extracted, the warning system for their diagnosis and differential diagnosis was established with the help of advanced information technology, Results The system had many functions, such as complete input, searching, statistics, analysis and warning on web. Preliminary verification was made in 314 cases which were classified to 49 kinds of contagious diseases, and the results showed that the coincidence rate of the first diagnosis of this system was 61,9%; the suggestive rate of the first three diagnoses was 78.1%, and that of the first five diagnoses was 86,6%. Conclusions The warning system for diagnosis and differential diagnosis of EID functions well, which is convenient, feasible and expanding, The system can accurately suggest impossible diagnosis and differential diagnosis, and provide guides for further examination and treatment. Special cases can be reported by national infectious reporting system so that an EID can be warned in advance.