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重组人脑利钠肽治疗AMI后急性左心室衰竭23例效果观察 被引量:9

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摘要 将43例急性心肌梗死(AMI)后急性左心室衰竭患者随机分为观察组23例和对照组20例,在常规纠正心衰治疗基础上分别静脉应用重组人脑利钠肽(rhBNP)和硝普钠。观察两组治疗前及治疗后30 min收缩压、心率、血氧饱和度和临床症状缓解(呼吸困难减轻,发绀消失,肺部罗音减少或消失)情况。结果用药后30 min观察组和对照组分别有20例和13例临床症状缓解(P<0.05),分别有2例和5例发生与用药有关的低血压反应(P(0.05);两组收缩压、心率均明显降低,血氧饱和度明显增高,但观察组效果优于对照组(P(0.05、0.01)。认为rhBNP治疗AMI后急性左心室衰竭疗效显著,安全性较高。
出处 《山东医药》 CAS 北大核心 2008年第23期55-56,共2页 Shandong Medical Journal
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