肝源性糖尿病53例临床分析

Clinical analysis of 53 cases of hepatogenous diabetes

目的:探讨肝源性糖尿病的临床特点、治疗及与慢性肝病临床类型的关系。方法:回顾性分析我院2003年1月～2006年12月诊治的53例肝源性糖尿病患者的临床资料。结果:肝源性糖尿病在急、慢性肝病中的发生率为31.36%(53/169),在肝硬化中的发生率高于慢性肝炎与慢性重型肝炎,差异有显著性(P<0.05)。血糖中、重度升高的比率,肝硬化高于慢性肝炎、慢性重型肝炎,差异有显著性(P<0.05)。通过饮食控制、护肝、抗病毒和(或)胰岛素治疗,除3例死于肝病严重并发症外,其余患者血糖水平均得到有效控制。结论:糖尿病轻重与肝损害程度呈正相关,治疗后随肝损害减轻而糖尿病症状逐步好转。

Objective： To investigate the clinical characteristics and treatment of hepatogenic diabetes and the relationship between hepatogenic diabetes and the type of chronic liver diseases. Methods： To analyze clinical data of 53 hepatogenic diabetes cases from January 2003 to December 2006 regressively. Results： The incidence of hepatogenous diabetes was 31.36%（53/169） in acute or chronic liver diseases. There was significant differences between hepatocirrhosis with chronic hepatitis and severe chronic hepatitis in the incidence of hepatogenic diabetes （P〈0.05） and percentage of prominently elevated blood sugar（P〈0.05）. Except 3 patients died of severe hepato-complications, all patients＇ blood sugars were controlled effectively by diet control,liver-protecting, antivirus and/or insulin therapy. Conclusion： It is suggested that the scale of the symptomatic severity of diabetes mellitus is positively related to degree of liver function damage. It would begetting Over gradually following the recovery of liver function after effective therapy.